首頁師資〉教師指導學生

楊孔嘉

楊孔嘉 (Kung-Chia Young, Ph.D.)

醫技所 教授 

分機:57875777    E-mail: t7908077@mail.ncku.edu.tw

個人網址:http://mt.ncku.edu.tw/files/11-1371-14490.php#tabs|Teacher:1

 

研究興趣

(1)C型肝炎病毒細胞培養之感染、複製、致病模式與抗病毒藥物

(2)C型肝炎病毒顆粒之型態與生物特性

(3)脂肪代謝與病毒感染之相關性

(4)載脂蛋白 (apolipoproteins)在病毒感染、代謝性疾病、肥胖之影響

近五年代表作

 

  1. Sun HY, Chen SF, Lai MD, Chang TT, Chen TL, Li PY, Shieh DB, Young KC. Comparative proteomic profiling of plasma very-low-density and low-density lipoproteins. Clin Chem Acta 2010 Mar 411:336-344. (correspondence)
  2. Cheng PN, Liu WC, Tsai HW, Wu IC, Chang TT, Young KC. Association of intrahepatic cccDNA reduction with the improvement of liver histology in chronic hepatitis B patients receiving oral antiviral agents. J Med Virol. 2011 Feb 83:602-607. (correspondence)
  3. Chang YS, Tsai CT, Huangfu CA, Huang WY, Lei HY, Lin CF, Su IJ, Chang WT, Wu PH, Chen YT, J Hung JH, Young KC, Lai MD. ACSL3 and GSK-3b are essential for lipid upregulation induced by endoplasmic reticulum stress in liver. J Cell Biochem 2011 Mar 112(3):881-93. (co-correspondence)
  4. Lee JW, Liao PC, Young KC, Chang CL, Chen SSL, Chang TT, Lai, MD, Wang SW. Identification of hnRNPH1, NF45, and C14orf166 as Novel Host Interacting Partners of the Mature Hepatitis C Virus Core Protein. J Proteome Res 2011 Aug 10(10):4522-4534.
  5. Sun HY, OuNY,WangSW, LiuWC, ChengTF, ShrSJ, SunKT, ChangTT, Young KC. Novel Nucleotide and Amino Acid Covariation between the 5’UTR and the NS2/NS3 proteins of Hepatitis C Virus: Bioinformatic and Functional Analyses. PLoS One 2011 Sep 6(9):e25530. (correspondence)
  6. Hsu MC, Chang CS, Lee KT, Sun HY, Tsai YS, Kuo PH, Young KC, Wu CH. Central obesity in males affected by a dyslipidemia-associated genetic polymorphism on APOA1/C3/A4/A5 gene cluster. Nutr Diabetes 2013 Mar Online 4;3:e61. doi: 10.1038/nutd.2013.2. (co-correspondence).
  7. Yang CL, Chiou YC, Chou CW, Young KC, Huang SJ, Liu CY. Point-of-care testing portable blood coagulation detectors using optical sensors. J Med Biol Eng 2013 May; 33(3):319-324 (co-correspondence)
  8. Hsu MC, Lee  KT, Hsiao  WC, Wu  CH, Sun  HY, Lin  IL, Young  KC. The dyslipidemia-associated SNP on the APOA1/C3/A5 gene cluster predicts post-surgery poor outcome in Taiwanese breast cancer patients: a 10-year follow-up study. BMC Cancer 2013 Jul; 13(1):330 (correspondence).
  9. Sun HY, Lin CC, Lee JC, Wang SW, Cheng PN, Wu IC, Chang TT, Lai MD, Shieh DB, Young KC. Very-low density lipoprotein/lipo-viro particles reverse lipoprotein lipase-mediated inhibition of hepatitis C virus infection via apolipoprotein C-III. Gut 2013 Aug;62(8):1193-203 (correspondence).
  10. Yang CL, Huang SJ, Chou CW, Chiou YC, Lin KP, Tsai MS, Young KC. Design and evaluation of a portable optical-based biosensor for testing whole blood prothrombin time. Talanta 2013 Nov; 116:704-711 (correspondence).