首頁師資〉專/兼任師資專長

黃步敏

黃步敏(Bu-Miin Huang, Ph.D.)

解剖學科細胞生物與解剖學研究所 教授

分機:5337    E-mail: bumiin@mail.ncku.edu.tw

個人網址: http://www.anatomy.ncku.edu.tw/people/bio.php?PID=4

研究興趣:

My major interest has been focused on the in vitro and in vivo regulation of anti-tumor effects in male reproductive systems by different factors, such as Chinese herbs, neuropeptides, anesthesia drugs and environmental toxicants.

近五年代表作:(* Corresponding author)  

  1. Kang FC, Wang SC, So EC, Chang MM, Wong KL, Cheng KS, Chen YC, Huang BM*. 2019. Propofol could increase caspases and MAPKs pathways and suppress Akt pathway to induce apoptosis in MA-10 mouse Leydig tumor cells. Oncology Reports, in press.
  2. Mu YF, Chen YH, Chang MM, Chen YC, Huang BM*. 2019. Arsenic compounds induce apoptosis through the caspase pathway in MA-10 Leydig tumor cells. Oncology Letters, in press.
  3. Chen YC, Huang BM. 2019. Primary culture of rat adrenocortical cells and the assays of steroidogenic functions. Journal of Visualized Experiments (JoVE), (145). doi: 10.3791/59016..
  4. Chang MM, Lai MS, Hong SY, Pan BS, Huang H, Yang SH, Wu CC, Sun HS, Jih-Ing Chuang JI, Wang CY, Huang BM*. 2018. FGF9/FGFR2 increases cell proliferation by activating ERK1/2, Rb/E2F1 and cell cycle pathways in mouse Leydig tumor cells. Cancer Science. 109:3503-3518.
  5. Kang FC, Wang SC, Chang MM, Pan BS, Wong KL, Cheng KS, So EC, Huang BM*. 2018. Midazolam activates caspase, MAPKs and ER stress pathways, and inhibits cell cycle and Akt pathway, to induce apoptosis in TM3 mouse Leydig progenitor cells. OncoTargets and Therapy. 11:1475-1490.
  6. Lien WC, Chen TY, Sheu SY, Lin TC, Kang FC, Yu CH, Kuan TS, Huang BM*, Wang CY*. 2018. 7-hydroxy-staurosporine, UCN-01, induces DNA damage response and autophagy in human osteosarcoma U2-OS cells. Journal of Cellular Biochemistry. 119(6):4729-4741.
  7. Syu JS, Baba T, Huang JY, Ogawa H, Hsieh CH, Hu JX, Chen TY, Lin TC, Tsuchiya M, Morohashi KI, Huang BM*, Lu FI, Wang CY. 2017. Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth. Scientific Reports. 7(1):240.
  8. Chen YC, Chen YH, Pan BS, Chang MM, Huang BM*. 2017. Functional study of Cordyceps sinensis and cordycepin in male reproduction – A review. Journal of Food and Drug Analysis. 25:197-205.
  9. Lai MS, Wang CY, Yang SH, Wu CC, H. Sun HS, Tsai SJ, Chuang JI, Chen YC, Huang BM*. 2016. The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes. Organogenesis. 14:1-17.
  10. So EC, Chen YC, Wang SC, Wu CC, Huang MC, Lai MS, Pan BS, Kang FC, Huang BM*. 2016. Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophage and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells. OncoTarget and Therapy. 9:2519-2533.
  11. Pan BS, Wang YK, Lai MS, Mu YF, Huang BM*. 2015. Cordycepin induced MA-10 mouse Leydig tumor cell apoptosis by regulating p38 MAPKs and PI3K/AKT signaling pathways. Scientific Reports. 5:13372. doi: 10.1038/srep13372.
  12. Kang FC, Chen PJ, Pan BS, Lai MS, Chen YC, Huang BM*. 2015. The apoptotic effect of cordycepin combined with cisplatin and/or taxol on MA-10 mouse Leydig tumor cells. OncoTargets and Therapy. 8:2345-2360.
  13. Chen YC, Liang YL, Huang YL, Huang BM*. 2015. Mechanism of Toona sinensis-stimulated adrenal steroidogenesis in primary rat adrenal cells. Journal of Functional Foods. 14:318-323.
  14. Lai MS, Cheng YS, Chen PR, Tsai SJ, Huang BM*. 2014. Fibroblast growth factor 9 activates Akt and MAPK pathways to stimulate steroidogenesis in mouse Leydig cells. PLoS One. 9(3):e90243.
  15. Chen YH, Hao LJ, Hung CP, Chen JW, Leu SF, Huang BM*. 2014. Apoptotic effect of cordycepin and cisplatin on OC3 human oral cancer cells. Chinese Journal of Integrative Medicine. 20(8):624-632.
  16. So EC, Lin YX, Tseng CH, Pan BS, Cheng KS, Wong KL, Hao LJ, Wang YK, Huang BM*. 2014. Midazolam induces apoptosis in MA-10 mouse Leydig tumor cells through caspase activation and the involvement of MAPK signaling pathway. OncoTargets and Therapy. 7:211-21.