首頁師資〉專/兼任師資專長

黃步敏

黃步敏(Bu-Miin Huang, Ph.D.)

解剖學科細胞生物與解剖學研究所 教授

分機:5337    E-mail: bumiin@mail.ncku.edu.tw

 

研究興趣:

My major interest has been focused on the in vitro and in vivo regulation of anti-tumor effects in male reproductive systems by different factors, such as Chinese herbs, neuropeptides, anesthesia drugs and environmental toxicants.

近五年代表作:(* Corresponding author) 

  1. Chang MM, Pan BS, Wang CY, Huang BM*. 2019. Cordycepin induced unfolded protein response-dependent cell death, and AKT/MAPK mediated drug resistance in mouse testicular tumor cells. Cancer Medicine. 8(8):3949-3964.
  2. Ho SY, Wu WS, Lin LC, Wu YH, Chiu HW, Yeh YL, Huang BM*, Wang YJ*. 2019. Cordycepin enhances radiosensitivity in oral squamous carcinoma cells by inducing autophagy and apoptosis through cell cycle arrest. International Journal of Molecular Sciences, 20(21). pii: E5366. doi: 10.3390/ijms20215366.
  3. Kang FC, Wang SC, So EC, Chang MM, Wong KL, Cheng KS, Chen YC, Huang BM*. 2019. Propofol could increase caspases and MAPKs pathways and suppress Akt pathway to induce apoptosis in MA-10 mouse Leydig tumor cells. Oncology Reports. 41:3565-3574.
  4. Mu YF, Chen YH, Chang MM, Chen YC, Huang BM*. 2019. Arsenic compounds induce apoptosis through the caspase pathway in MA-10 Leydig tumor cells. Oncology Letters. 18:944-954.
  5. Chen YC, Huang BM. 2019. Primary culture of rat adrenocortical cells and the assays of steroidogenic functions. Journal of Visualized Experiments (JoVE), (145). doi: 10.3791/59016..
  6. Chang MM, Lai MS, Hong SY, Pan BS, Huang H, Yang SH, Wu CC, Sun HS, Jih-Ing Chuang JI, Wang CY, Huang BM*. 2018. FGF9/FGFR2 increases cell proliferation by activating ERK1/2, Rb/E2F1 and cell cycle pathways in mouse Leydig tumor cells. Cancer Science. 109:3503-3518.
  7. Kang FC, Wang SC, Chang MM, Pan BS, Wong KL, Cheng KS, So EC, Huang BM*. 2018. Midazolam activates caspase, MAPKs and ER stress pathways, and inhibits cell cycle and Akt pathway, to induce apoptosis in TM3 mouse Leydig progenitor cells. OncoTargets and Therapy.11:1475-1490.
  8. Lien WC, Chen TY, Sheu SY, Lin TC, Kang FC, Yu CH, Kuan TS, Huang BM*, Wang CY*. 2018. 7-hydroxy-staurosporine, UCN-01, induces DNA damage response and autophagy in human osteosarcoma U2-OS cells. Journal of Cellular Biochemistry. 119(6):4729-4741.
  9. Syu JS, Baba T, Huang JY, Ogawa H, Hsieh CH, Hu JX, Chen TY, Lin TC, Tsuchiya M, Morohashi KI, Huang BM*, Lu FI, Wang CY. 2017. Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth. Scientific Reports. 7(1):240.
  10. Chen YC, Chen YH, Pan BS, Chang MM, Huang BM*. 2017. Functional study of Cordyceps sinensis and cordycepin in male reproduction – A review. Journal of Food and Drug Analysis. 25:197-205.
  11. Lai MS, Wang CY, Yang SH, Wu CC, H. Sun HS, Tsai SJ, Chuang JI, Chen YC, Huang BM*. 2016. The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes. Organogenesis. 14:1-17.
  12. So EC, Chen YC, Wang SC, Wu CC, Huang MC, Lai MS, Pan BS, Kang FC, Huang BM*. 2016. Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophage and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells. OncoTarget and Therapy. 9:2519-2533.
  13. Pan BS, Wang YK, Lai MS, Mu YF, Huang BM*. 2015. Cordycepin induced MA-10 mouse Leydig tumor cell apoptosis by regulating p38 MAPKs and PI3K/AKT signaling pathways. Scientific Reports. 5:13372. doi: 10.1038/srep13372.
  14. Kang FC, Chen PJ, Pan BS, Lai MS, Chen YC, Huang BM*. 2015. The apoptotic effect of cordycepin combined with cisplatin and/or taxol on MA-10 mouse Leydig tumor cells. OncoTargets and Therapy. 8:2345-2360.
  15. Chen YC, Liang YL, Huang YL, Huang BM*. 2015. Mechanism of Toona sinensis-stimulated adrenal steroidogenesis in primary rat adrenal cells. Journal of Functional Foods. 14:318-323.