首頁師資〉專/兼任師資專長

黃步敏

黃步敏(Bu-Miin Huang, Ph.D.)

解剖學科細胞生物與解剖學研究所 教授

分機:5337    E-mail: bumiin@mail.ncku.edu.tw

個人網址: http://www.ncku.edu.tw/~anatomy/

 

研究興趣

 

   My major interest has been focused on the in vitro and in vivo regulation of steroidogenesis in male and female reproductive systems by different factors such as Chinese herbs, neuropeptides, drugs and environmental toxicants. Also, the apoptotic effects of anti-tumor drugs and Chinese herbs on tumor cells in reproductive system and/or head and neck regions are being studied. The signal transduction pathways involved in the regulation of cell steroidogenesis and the apoptotic pathway involved in tumor cell death, apoptosis, in cellular and molecular levels are currently being investigated.

 

近五年代表作

 

  1. Lai MS, Cheng YS, Chen PR, Tsai SJ, Huang BM. 2014. Fibroblast growth factor 9 activates Akt and MAPK pathways to stimulate steroidogenesis in mouse Leydig cells. PLoS One. 9(3):e90243. (SCI).
  2. So EC, Lin YX, Tseng CH, Pan BS, Cheng KS, Wong KL, Hao LJ, Wang YK, Huang BM. 2014. Midazolam induces apoptosis in MA-10 mouse Leydig tumor cells through caspase activation and the involvement of MAPK signaling pathway. OncoTargets and Therapy. 7:211-21. (SCI).
  3. Chen YH, Wang JY, Pan BS, Mu YF, Lai MS, So EC, Wong TS, Huang BM. 2013. Cordycepin enhances cisplatin apoptotic effect through caspase/MAPK pathways in human head and neck tumor cells. OncoTargets and Therapy. 6:983-98. (SCI).
  4. Pao HY, Pan BS, Leu SF, Huang BM. 2012. Cordycepin Stimulated Steroidogenesis in MA-10 Mouse Leydig Tumor Cells through Protein Kinase C Pathway. Journal of Agricultural and Food Chemistry. 60:4905-4913. (SCI).
  5. Pan BS, Lin CY, Huang BM. 2011.The effect of cordycepin on steroidogenesis and apoptosis in MA-10 mouse Leydig Tumor Cells. Evidence Based Complementary and Alternative Medicine. On-line. (SCI).
  6. Chen YH, Leu SF, Jen CY, Huang BM. 2011. Effects of sesamol on apoptosis and steroidogenesis in MA-10 mouse Leydig tumor cells. Journal of Agricultural and Food Chemistry. 59:9885-9891. (SCI).
  7. Leu SF, Poon SL, Pao HS, Huang BM. 2011. The in vivo and in vitro stimulatory effects of cordycepin on mouse Leydig cell steroidogenesis. Bioscience. Biotechnology, and Biochemistry. 75:723-731. (SCI).
  8. Chen YC, Huang BM. 2010. Regulatory mechanisms of Cordyceps sinensis on steroidogenesis in MA-10 mouse Leydig tumor cells. Bioscience, Biotechnology, and Biochemistry. 74:1855-1859. (SCI).
  9. Lin YM, Tsai CC, Chung CL, Chen PL, Sun HS, Tsai SJ, Huang BM. 2010. Fibroblast growth factor 9 stimulates steroidogenesis in postnatal Leydig cells. International Journal of Andrology. 33:545-553. (SCI).
  10. So EC, Chang YT, Hsing CH, Poon PWF, Leu, SF, Huang BM. 2010. The effect of midazolam on mouse Leydig cell steroidogenesis and apoptosis. Toxicology Letters. 192:169-178. (SCI).
  11. Jen CY, Lin CY, Leu SF, Huang BM. 2009. Cordycepin induced MA-10 mouse Leydig tumor cell apoptosis through caspase-9 pathway. Evidence Based Complementary and Alternative Medicine. On-line. (SCI).
  12. Hsiao JR, Leu SF, Huang BM. 2009. Apoptotic mechanism of paclitaxel-induced cell death in human head and neck tumor cell lines. Journal of Oral Pathology and Medicine. 38:188-97. (SCI).