首頁師資〉專/兼任師資專長

江美治

江美治  (Jiang, Meei-Jyh, Ph.D.)

解剖學科暨細胞暨解剖學研究所 副教授

分機:5331    E-mail: mjiang@mail.ncku.edu.tw

個人網址:http://www.ncku.edu.tw/~anatomy/

 

研究興趣

  1. 血管窄化所誘發的腹主動脈瘤發生的機制: 以血管窄化誘發蘭嶼迷你豬形成腹主動脈瘤為動物模式,配合演進過程中細胞與基因表現的變化,來探討腹主動脈瘤發生與演進的機制。
  2. 平滑肌細胞老化的分子機制:探討氧化壓力與產生氧活性中間物質(reactive oxygen species)的酵素(NADPH oxidase)及胞器(mitochondria)在平滑肌細胞老化的角色。
  3. 凝血酶調節素(thrombomodulin)在血管平滑肌細胞的表現與功能:探討凝血酶調節素在平滑肌細胞表現的調控及其調節血管平滑肌細胞移行的作用機制。

近五年代表作

 

  1. Lin PY, Wu YT, Lin GC, Shih YH, Sampilvanjil A, Chen LR, Yang YJ, Wu HL, Jiang MJ. (2013) Coarctation-induced degenerative abdominal aortic aneurysm in a porcine model.,J Vasc Surg,57,pp806-815 (SCI)
  2. Cheng JC, Cheng HP, Tsai IC,Jiang MJ. (2013),ROS-mediated down-regulation of MYPT1 in smooth muscle cells: a potential mechanism for the aberrant contractility in atherosclerosis.,Lab Invest,doi:10.1038/labinvest.2013.40 (SCI)
  3. Tsai MH, Jiang MJ (2010). Reactive oxygen species are involved in regulating α1-adrenocptor-activated vascular smooth muscle contraction. J Biomed Sci 17: 67-76.
  4. Lo IC, Lin TM, Chou LH, Liu SL, Wu LW, Shi GY, Wu HL, Jiang MJ (2009). Ets-1 mediates platelet-derived growth factor-BB-induced thrombomodulin expression in human vascular smooth muscle cells. Cardiovasc Res 81: 771-779.
  5. Wing LYC, Chen YC, Shih YY, Cheng JC, Lin YJ, Jiang MJ (2009). Effects of oral estrogen on aortic ROS-generating and –scavenging enzymes and atherosclerosis in apoE-deficient mice. Exp Biol Med 234: 1037-1046.