首頁師資〉教師指導學生

林以行

林以行  (Lin, Yee-Shin, Ph.D.)

微免所 教授分機:5646   E-mail: yslin1@mail.ncku.edu.tw 

研究興趣

  1. 登革病毒致病機制及抗病毒策略和疫苗研發。
  2. A群鏈球菌感染之致病機轉及抗發炎藥物之保護作用。
  3. 細胞凋亡和細胞自噬機制及訊息傳遞。 

近五年代表作

 

  1. Cheng Y. L., C. F. Kuo, S. L. Lu, O. Hiroko, Y. N. Wu, C. L. Hsieh, T. Noda, S. R. Wu, R. Anderson, C. F. Lin, C. L. Chen, J. J. Wu, and Y. S. Lin. 2019. Group A streptococcus induces LAPosomes via SLO/β1 integrin/NOX2/ROS pathway in endothelial cells that are ineffective in bacterial killing and suppress xenophagy. mBio 10:e02148-19.
  2. Kao, Y. S., C. Y. Yu, H. J. Huang, S. M. Tien, W. Y. Wang, M. Yang, R. Anderson, T. M. Yeh, Y. S. Lin, and S. W. Wan. 2019. Combination of modified NS1 and NS3 as a novel vaccine strategy against dengue virus infection. J. Immunol. 203:1909-1917.
  3. Chen, C. L., M. H. Cheng, C. F. Kuo, Y. L. Cheng, M. H. Li, C. P. Chang, J. J. Wu, R. Anderson, S. Wang, P. J. Tsai, C. C. Liu, and Y. S. Lin. 2018. Dextromethorphan attenuates NADPH oxidase-regulated GSK-3 and NF-B activation and reduces nitric oxide production in Group A Streptococcal infection. Antimicrob. Agent. Chemother. 62(6).
  4. Wan, S. W., P. W. Chen, C. Y. Chen, Y. C. Lai,Y. T. Chu, C. Y. Hung,H. Lee, H. F. Wu, Y. C. Chuang, J. Lin, C. P. Chang, S. Wang, C. C. Liu, T. S. Ho, C. F. Lin, C. K. Lee, B. A. Wu-Hsieh,R. Anderson, T. M. Yeh, and Y. S. Lin. 2017. Therapeutic effects of monoclonal antibody against dengue virus NS1 in a STAT1 knockout mouse model of dengue infection. J. Immunol. 199:2834-2844.
  5. Cheng, Y. L., Y. W. Wu, C. F. Kuo, S. L. Lu, F. T. Liu, R. Anderson, C. F. Lin, Y. L. Liu, W. Y. Wang, Y. D. Chen, P. X. Zheng, J. J. Wu, and Y. S. Lin. 2017. Galectin-3 inhibits Galectin-8/Parkin-mediated ubiquitination of Group A Streptococcus. mBio. 8:e00899-17.
  6. Zainal, N., C. P. Chang, Y. L. Cheng, Y. W. Wu, R. Anderson, S. W. Wan,C. L. Chen, T. S. Ho, S. AbuBakar, and Y. S. Lin. 2017. Resveratrol treatment reveals a novel role for HMGB1 in regulation of the type 1 interferon response in dengue virus infection. Sci. Rep.7:42998.
  7. Chen, Y. D., Y. T. Fang, Y. L. Cheng, C. F. Lin, L. J. Hsu, S. Y. Wang, R. Anderson, C. P. Chang, and Y. S. Lin. 2017. Exophagy of annexin A2 via RAB11, RAB8A and RAB27A in IFN-g-stimulated lung epithelial cells. Sci. Rep. 7:5676.
  8. Chen, Y. D., Y. T. Fang, C. P. Chang,C. F. Lin, L. J. Hsu, S. R. Wu, Y. C. Chiu, R. Anderson, and Y. S. Lin. 2017. S100A10 regulates ULK1 localization to ER-mitochondria contact sites in IFN--triggered autophagy. J. Mol. Biol. 429:142-157.
  9. Wan, S. W.,Y. W. Yang, Y. T. Chu, C. F. Lin, C. P. Chang, T. M. Yeh, R. Anderson, and Y. S. Lin. 2016. Anti-dengue virus nonstructural protein 1 antibodies contribute to platelet phagocytosis by macrophages. Thromb. Haemost. 115:646-656.
  10. Chen, C. L., Y. Y. Wu, C. F. Lin, C. F. Kuo, C. L. Han, S. Wang, W. J. Chuang, C. Y. Chen, J. J. Wu, P. J. Tsai, C. C. Liu, and Y. S. Lin. 2016. Streptococcal pyrogenic exotoxin B inhibits apoptotic cell clearance by macrophages through protein S cleavage. Sci. Rep. 6:26026.