首頁師資〉教師指導學生

許桂森

許桂森 (Hsu, Kuei-Sen, Ph.D.)

藥理所 講座教授    分機:5498     E-mail: richard@mail.ncku.edu.tw

個人網頁:https://pharma.ncku.edu.tw/members_view.php?qid=4&lmenuid=11&smenuid=5&lang=tw

研究興趣:

  1. 神經突觸可塑性(synpatic plasticity)及結構可塑性(structural plasticity)之調控因子及分子作用機轉之研究。
  2. 壓力(Stress)及催產素(Oxytocin)對於神經突觸可塑性及神經元新生作用影響之研究。

    3. 個體壓力感受性差異之探討。

    4. 記憶形成即遺忘之分子機制探討。

研究方法電氣生理學、蛋白化學、神經化學、分子生物學、光遺傳學

近五年代表作:

  1. Chiou CH, Chen CC, Tsai TC, Huang CC, Chou D, Hsu KS.* (2016) Alleviating bone cancer-induced mechanical hypersensitivity by inhibiting neuronal activity in the anterior cingulate cortex. Anesthesiology 125:779-792.
  2. Lin YT, Chen CC, Huang CC, Nishimori K, Hus KS.* (2017) Oxytocin stimulates hippocampal neurogenesis via oxytocin receptor expressed in CA3 pyramidal neurons. Nat. Commun. 8:537.
  3. Wu YJ, Lin CC, Yeh CM, Chien ME, Tsao MC, Tseng P, Huang CW, Hsu KS.* (2017) Repeated transcranial direct current stimulation improves decline in cognitive function and synaptic plasticity in the prefrontal cortex of streptozotocin-induced diabetic rats. Brain Stimul. 10(6):1079-1087.
  4. Lin YT, Hsieh TY, Tsai TC, Chen CC, Huang CC, Hsu KS.* (2018) Conditional deletion of hippocampal CA2/CA3a oxytocin receptor impairs the persistence of long-term social recognition memory in mice. J. Neurosci.38(5):1218-1231.
  5. Huang, W.Y., Lin, S., Chen, H.Y., Chen, Y.P., Chen, T.Y., Hsu, K.S.* and Wu, H.M.* (2018) NADPH oxidases as potential pharmacologic targets against increased seizure susceptibility after systemic inflammation. J. Neuroinflamm. 15:140.
  6. Lin, Y.T. and Hus, K.S.* (2018) Oxytocin receptor signaling in the hippocampus: role in regulating neuronal excitability, network oscillatory activity, synaptic plasticity and social memory. Prog. Neurobiol. 171:1-14.
  7. Yu, T.H., Wu, Y.J.,  Chien, M.E. and Hsu, K.S.* (2019) Transcranial direct current stimulation induces hippocampal metaplasticity mediated by brain-derived neurotrophic factor. Neuropharmacology144:358-367.