首頁師資〉教師指導學生

許桂森

許桂森 (Hsu, Kuei-Sen, Ph.D.)

藥理所 講座教授    分機:5498     E-mail: richard@mail.ncku.edu.tw

個人網頁:http://pharma.ncku.edu.tw/files/15-1367-161285,c14108-1.php?Lang=zh-tw

研究興趣

  1. 神經突觸可塑性(synpatic plasticity)及結構可塑性(structural plasticity)之調控因子及分子作用機轉之研究。
  2. 壓力(Stress)及催產素(Oxytocin)對於神經突觸可塑性及神經元新生作用影響之研究。
  3. 個體壓力感受性差異之探討。
  4. 記憶形成即遺忘之分子機制探討。 

研究方法電氣生理學、蛋白化學、神經化學、分子生物學、光遺傳學

近五年代表作

  1. Yang CH, Huang CC, and Hsu, K. S.* (2012) A critical role for protein tyrosine phosphatase nonreceptor type 5 in determining individual susceptibility to develop stress-related cognitive and morphological changes. J Neurosci. 32(22):7550-7562.
  2.  Lin YT, Huang CC, Hsu KS.*(2012) Oxytocin promotes long-term potentiation by enhancing epidermal growth factor receptor-mediated local translation of protein kinase Mz. J Neurosci, 32(44):15476-15488.
  3. Chiou CH, Chen CC, Tsai TC, Huang CC, Chou D, Hsu KS.* (2016) Alleviating bone cancer-induced mechanical hypersensitivity by inhibiting neuronal activity in the anterior cingulate cortex. Anesthesiology 125:779-792.
  4. Lin YT, Chen CC, Huang CC, Nishimori K, Hus KS.* (2017) Oxytocin stimulates hippocampal neurogenesis via oxytocin receptor expressed in CA3 pyramidal neurons. Nat. Commun. 8:537.
  5. Wu YJ, Lin CC, Yeh CM, Chien ME, Tsao MC, Tseng P, Huang CW, Hsu KS.* (2017) Repeated transcranial direct current stimulation improves decline in cognitive function and synaptic plasticity in the prefrontal cortex of streptozotocin-induced diabetic rats. Brain Stimul. 10(6):1079-1087.
  6. Lin YT, Hsieh TY, Tsai TC, Chen CC, Huang CC, Hsu KS.* (2018) Conditional deletion of hippocampal CA2/CA3a oxytocin receptor impairs the persistence of long-term social recognition memory in mice. J. Neurosci.38(5):1218-1231.