首頁師資〉專/兼任師資專長

許桂森

許桂森 (Hsu, Kuei-Sen, Ph.D.)

藥理所 講座教授    分機:5498     E-mail: richard@mail.ncku.edu.tw

研究興趣

1. 神經突觸可塑性(synpatic plasticity)及結構可塑性(structural plasticity)之調控因子及分子作用機轉之研究。

2. 壓力(Stress)及催產素(Oxytocin)對於神經突觸可塑性及神經元新生作用影響之研究。

3. 個體壓力感受性差異之探討。

4. 記憶形成即遺忘之分子機制探討。

研究方法電氣生理學、蛋白化學、神經化學、分子生物學、光遺傳學

近五年代表作

  1. Lin YT, Chen CC, Huang CC, Nishimori K, Hus KS.* (2017) Oxytocin stimulates hippocampal neurogenesis via oxytocin receptor expressed in CA3 pyramidal neurons. Nat. Commun. 8:537.
  2. Wu YJ, Lin CC, Yeh CM, Chien ME, Tsao MC, Tseng P, Huang CW, Hsu KS.* (2017) Repeated transcranial direct current stimulation improves decline in cognitive function and synaptic plasticity in the prefrontal cortex of streptozotocin-induced diabetic rats. Brain Stimul. 10(6):1079-1087.
  3. Lin YT, Hsieh TY, Tsai TC, Chen CC, Huang CC, Hsu KS.* (2018) Conditional deletion of hippocampal CA2/CA3a oxytocin receptor impairs the persistence of long-term social recognition memory in mice. J. Neurosci.38(5):1218-1231.
  4. Lin YT, Hus KS.* (2018) Oxytocin receptor signaling in the hippocampus: role in regulating neuronal excitability, network oscillatory activity, synaptic plasticity and social memory. Prog. Neurobiol. 171:1-14.
  5. Yang CY, Yu TH, Wen WL, Lin P, Hus KS.* (2019) Conditional deletion of CC2D1A reduces hippocampal synaptic plasticity and impairs cognitive function through Rac1 hyperactivation. J. Neurosci. 39(25):4959-4975.
  6. Huang WY, Liu KH, Lin SK, Chen TY, Chen HY, Tseng CY, Chen YP, Wu HM, Hsu KS.*(2020) NADPH oxidase 2 as a potential therapeutic target for protection against cognitive deficits following systemic inflammation in mice. Brain Behav Immun. 84:242-252.