首頁師資〉專/兼任師資專長

黃金鼎

黃金鼎  (Huang, Jin-ding, Ph.D.)

藥理所 教授       

分機5500    E-mail: jinding@mail.ncku.edu.tw

個人網址:

http://www.ncku.edu.tw/~pharma/pharmacology/main/3_teachers/3.html

 

研究興趣

 

1.      藥品及毒物的分佈、代謝、吸收、作用的機轉及調控。

2.      Mechanism and regulation of disposition, absorption, metabolism, and action of xenobiotics.

 

近五年代表作

1.      Y. P. Lim, C. H. Liu, L. J. Shyu, J. D. Huang (2005) Functional characterization of a novel polymorphism of pregnane X receptor, Q158K, in Chinese subjects.Pharmacogenet. Genom. 15, 337-341.

2.      S. J. Tzeng, W. C. Chang, J. D. Huang (2005) Transcriptional regulation of the rat Mrp3 gene promoter by the specificity protein (Sp) family members and CCAAT/enhancer binding proteins. J. Biomed. Sci. 12, 741-761.

3.      C. H. Liu, K. Peck, J. D. Huang, M. S. Lin, C. H. Wang, W. P. Hsu, H. W. Wang, H. L. Lee, M. L. Lai (2005) Screening CYP3A SNP’s in a Han Chinese population with a genotyping chip. Pharmacogenomics 6, 731-747.

4.      W. J. Lu, K. Huang, M. L. Lai, J. D. Huang (2006) Erythromycin alters pharmacokinetics of bromocriptine by inhibition of OATP-C-mediated uptake. Clin. Pharmacol. Ther. 80, 421-422.

5.      Y. P. Lim, J. D. Huang (2007) Pregnane X-receptor (PXR) polymorphism affects CYP3A4 induction through ligand-dependent interaction with SRC-1. Pharmacogenet. Genom. 17, 369-382.