首頁師資〉教師指導學生

王仰高

王仰高 (Yang-Kao Wang. Ph.D.)                                     

細胞生物及解剖學研究所    助理教授  分機:5333        Email: humwang@mail.ncku.edu.tw

個人網址:http://www.anatomy.ncku.edu.tw/people/bio.php?PID=94

專長與研究興趣:

  1. 細胞外微環境 (物理及化學因子)如何調控骨髓間質幹細胞之生長及分化
  2. 細胞骨架之收縮力在骨髓間質幹細胞分化的影響
  3. 神經突觸生長之調控

近五年代表作:

  1. Liu CY, Lin HH, Tang MJ, Wang YK. Vimentin contributes to epithelial-mesenchymal transition cancer cell mechanics by mediating cytoskeletal organization and focal adhesion maturation. Oncotarget, 2015, accepted. (Corresponding)
  2. Han HI, Wang YK, Hsu CK, Ho YT, Huang YW, Chiu WT, Lin HH, Cheng CM, Tang MJ. Mechanical coupling of cytoskeletal elasticity and force generation is crucial for understanding the migration nature of keloid fibroblasts. Exp Dermatol, 2015, accepted.
  3. So EC, Lin YX, Pan BS, Cheng KS, Wong KL, Hao LJ, Wang YK* and Huang BM*. Midazolam stimulates caspase and MAPK, but inhibits Akt, pathways to induce apoptosis in MA-10 mouse Leydig cells.,OncoTargets and Therapy 7:211-7, 2014. (Corresponding)
  4. Wu KC, Tseng CL, Wu CC, Kao FC, Tu YK, So EC, Wang YK. Nanotechnology in the regulation of stem cell behavior. Sci Tech Adv Mater,14:054401, 2013. (Corresponding)
  5. Lee YH, Huang JR, Wang YK, and Lin KH. Three-dimensional fibroblast morphology on compliant and negatively curved substrates. Integrative Biol. 5:1447-55, 2013.
  6. Wang YK, Chen CS. Cell adhesion and mechanical stimulation in the regulation of mesenchymal stem cell differentiation. J Cell Mol Med.17: 823-32, 2013. (Corresponding)
  7. Wang YK*, Yu X*, Cohen DM, Wozniak MA, Yang MT, Gao L, Eyckmans J, and Chen CS. BMP-2-Induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tension. Stem Cell Dev. 21: 1176-86, 2012.
  8. Yang MT, Fu J, Wang YK, Desai R, and Chen CS. Assaying stem cell mechanoniology on microfabricated elastomeric substrates with geometrically modulated rigidity. Nat Protocol. 6:187- 213, 2011.
  9. Fu JP*, Wang YK*, Yang MT, Desai, RD, Yu X, Liu ZJ, Chen CS. Mechanical regulation of cell function using geometrically modulated elastomeric substrates. Nat Methods. 7: 733-6, 2010. (*, equal contribution)

 

  1. Liu CY, Lin HH, Tang MJ, Wang YK. Vimentin contributes to epithelial-mesenchymal transition cancer cell mechanics by mediating cytoskeletal organization and focal adhesion maturation. Oncotarget, 2015, accepted. (Corresponding)
  2. Han HI, Wang YK, Hsu CK, Ho YT, Huang YW, Chiu WT, Lin HH, Cheng CM, Tang MJ. Mechanical coupling of cytoskeletal elasticity and force generation is crucial for understanding the migration nature of keloid fibroblasts. Exp Dermatol, 2015, accepted.
  3. So EC, Lin YX, Pan BS, Cheng KS, Wong KL, Hao LJ, Wang YK* and Huang BM*. Midazolam stimulates caspase and MAPK, but inhibits Akt, pathways to induce apoptosis in MA-10 mouse Leydig cells.,OncoTargets and Therapy 7:211-7, 2014. (Corresponding)
  4. Wu KC, Tseng CL, Wu CC, Kao FC, Tu YK, So EC, Wang YK. Nanotechnology in the regulation of stem cell behavior. Sci Tech Adv Mater,14:054401, 2013. (Corresponding)
  5. Lee YH, Huang JR, Wang YK, and Lin KH. Three-dimensional fibroblast morphology on compliant and negatively curved substrates. Integrative Biol. 5:1447-55, 2013.
  6. Wang YK, Chen CS. Cell adhesion and mechanical stimulation in the regulation of mesenchymal stem cell differentiation. J Cell Mol Med.17: 823-32, 2013. (Corresponding)
  7. Wang YK*, Yu X*, Cohen DM, Wozniak MA, Yang MT, Gao L, Eyckmans J, and Chen CS. BMP-2-Induced signaling and osteogenesis is regulated by cell shape, RhoA/ROCK, and cytoskeletal tension. Stem Cell Dev. 21: 1176-86, 2012.
  8. Yang MT, Fu J, Wang YK, Desai R, and Chen CS. Assaying stem cell mechanoniology on microfabricated elastomeric substrates with geometrically modulated rigidity. Nat Protocol. 6:187- 213, 2011.
  9. Fu JP*, Wang YK*, Yang MT, Desai, RD, Yu X, Liu ZJ, Chen CS. Mechanical regulation of cell function using geometrically modulated elastomeric substrates. Nat Methods. 7: 733-6, 2010. (*, equal contribution)