首頁師資〉教師指導學生

王家義

王家義  (Wang, Chia-Yih, Ph.D.)

解剖學科 / 細胞生物暨解剖學研究所 助理教授    電話分機:5338    E-mail: b89609046@gmail.com

個人網頁:http://www.anatomy.ncku.edu.tw/people/bio.php?PID=89

研究興趣

  1. 探討DNA損傷調控蛋白Chk2如何監控G0/G1細胞週期之進行。
  2. DNA損傷引發之異常有絲分裂對於腎上腺皮質癌之毒殺機制。
  3. 探討氯奎寧(Chloroquine)引發視網膜病變的分子機制。

近五年代表作

  1. Takashi Baba, Hiroyuki Otake, Tetsuya Sato, Kanako Miyabayashi, Yurina Shishido, Chia-Yih Wang, Yuichi Shima, Hiroshi Kimura, Mikako Yagi, Yasuhiro Ishihara, Shinjiro Hino, Hidesato Ogawa, Mitsuyoshi Nakao, Takeshi Yamazaki, Dongchon Kang, Yasuyuki Ohkawa, Mikita Suyama, Bon-chu Chung, and Ken-ichirou Morohashi (2014) Glycolytic genes as the targets of a nuclear receptor Ad4BP/SF-1, Nature Communications, Epub ahead of print.
  2. Chia-Yih Wang, Eva Yi-Hsuan Huang, Sheng-chieh Huang, and Bon-chu Chung (2014) DNA-PK/Chk2 induces centrosome amplification during prolonged replication stress, Oncogene, Epub ahead of print.
  3. Chia-Yih Wang, Wei-Yi Chen, Pao-Yen Lai, and Bon-chu Chung (2013) Distinct Functions of Steroidogenic Factor-1 (NR5A1) in the nucleus and the centrosome, Molecular and Cellular Endocrinology, 371, 1-2, pp148-153
  4. Chia-Yih Wang, Yung-Hsin Kao, Pao-Yen Lai, Wei-Yi Chen, and Bon-chu Chung (2013) Steroidogenic Factor-1 (NR5A1) maintains centrosome homeostasis in steroidogenic cells by restricting centrosomal DNA-PK activation, Molecular and Cellular Biology, 33, 3, pp476-484
  5. Pao-Yen Lai*, Chia-Yih Wang*, Wei-Yi Chen, Yung-Hsin Kao, Huei-Man Tsai, Taro Tachibana, Wen-Chang Chang and Bon-chu Chung (*: co-first autors) (2011) Steroidogenic Factor 1 (NR5A1) resides in centrosomes and maintains genomic stability by controlling centrosome homeostasis, Cell Death and Differentiation, 18, 12, pp1836-1844