首頁師資〉專/兼任師資專長

王家義

王家義(Wang, Chia-Yih, Ph.D.)

細胞生物暨解剖學研究所  助理教授分機:5338   Email: b89609046@gmail.com

個人網頁:http://www.anatomy.ncku.edu.tw/people/bio.php?PID=89

研究興趣:

  1. To investigate the novel function of Chk2 in preventing tumorigenesis.
  2. To study the molecular mechanism by which autophagy regulates steroidogenic cell growth and differention.
  3. To study the role of primary cilia in controlling cell fate determination.

近五年代表作:

  1. Jhih-Siang Syu, Takashi Baba, Jyun-Yuan Huang, Hidesato Ogawa, Chi-Han Hsieh, Jin-Xian Hu, Ting-Yu Chen,Tzu-Chien Lin, Megumi Tsuchiya, Ken-Ichirou Morohashi, Bu-Miin Huang, Fu-l Lu and Chia-Yih Wang* (2017) Lysosomal activity maintains glycolysis and cyclin E1 expression by mediating Ad4BP/SF-1 stability for proper steroidogenic cell growth, Scientific Reports, Accepted
  2. 106   Yi-Ru Shen, Han-Yu Wang, Yung-Che Kuo, Shih-Chuan Shih, Chun-Hua Hsu, Yet-Ran Chen, Shang-Rung Wu, Chia-Yih Wang*, Pao-Lin Kuo* (2017) SEPT12 Phosphorylation Results in Loss of the Septin Ring/Sperm Annulus, Defective Sperm Motility and Poor Male Fertility, PLOS Genetics, Accepted
  3. Chia-Yih Wang, Hui-Ling Tsai, Jhih-Siang Syu, Ting-Yu Chen, Mei-Tsz Su (2016) Primary cilium-regulated EG-VEGF signaling facilitates trophoblast invasion, Journal of Cellular Physiology, Accepted
  4. Meng-Shao Lai, Chia-Yih Wang, Shang-Hsun Yang, Chia-Ching Wu, H. Sunny Sun, Shaw-Jenq Tsai, Jih-Ing Chuang, Yung-Chia Chen, Bu-Miin Huang (2016) The expression profiles of fibroblast growth factor 9 and its receptors in developing mice testes, Organogenesis ,Accepted
  5. Ting-Yu Chen, Jhih-Siang Syu, Tzu-Chien Lin, Hui-ling Cheng, Fu-l Lu and Chia-Yih Wang* (2015) Chloroquine alleviates etoposide-induced centrosome amplification by inhibiting CDK2 in adrenocortical tumor cells, Oncogenesis,4,ppe180
  6. Yang-Chi Fan, Shi-Yuan Sheu, Hong-Thih Lai, Ming-Huang Chang, Pei-Heng Chen, Yi-Chih Lei, Chia-Yih Wang*, Tzong-Fu Kuo* (*corresponding author) (2015) Residue Depletion Study of Danofloxacin in Cultured Tilapia (Oreochromis mossambicus), The Journal of AOAC International, Accepted
  7. Ting-Yu Chen, Jhih-Siang Syu, Tsung-Yu Han, Hui-ling Cheng, Fu-I Lu and Chia-Yih Wang* (2015) Cell cycle-dependent localization of Dynactin subunit p150glued at centrosome, Journal of Cellular Biochemistry, Epub ahead of print.9. Chia-Yih Wang, Eva Yi-Hsuan Huang, Sheng-chieh Huang, and Bon-chu Chung (2015) DNA-PK/Chk2 induces centrosome amplification during prolonged replication stress, Oncogene, ,34,10,pp1263-1269 11. Takashi Baba, Hiroyuki Otake, Tetsuya Sato, Kanako Miyabayashi, Yurina Shishido, Chia-Yih Wang, Yuichi Shima, Hiroshi Kimura, Mikako Yagi, Yasuhiro Ishihara, Shinjiro Hino, Hidesato Ogawa, Mitsuyoshi Nakao, Takeshi Yamazaki, Dongchon Kang, Yasuyuki Ohkawa, Mikita Suyama, Bon-chu Chung, and Ken-ichirou Morohashi (2014) Glycolytic genes as the targets of a nuclear receptor Ad4BP/SF-1, Nature Communications, 5,3634,pp1-13 13. Chia-Yih Wang, Yung-Hsin Kao, Pao-Yen Lai, Wei-Yi Chen, and Bon-chu Chung (2013) Steroidogenic Factor-1 (NR5A1) maintains centrosome homeostasis in steroidogenic cells by restricting centrosomal DNA-PK activation, Molecular and Cellular Biology, 33, 3, pp476-484
  8. 12. Chia-Yih Wang, Wei-Yi Chen, Pao-Yen Lai, and Bon-chu Chung (2013) Distinct Functions of Steroidogenic Factor-1 (NR5A1) in the nucleus and the centrosome, Molecular and Cellular Endocrinology, 371, 1-2, pp148-153
  9. 10. Chia-Yih Wang, Pao-Yen Lai, Ting-Yu Chen and Bon-chu Chung (2014) NR5A1 prevents centriole splitting by inhibiting centrosomal DNA-PK activation and beta-catenin accumulation, Cell Communication and Signaling,12,1,pp55-
  10. 8. Yung-Che Kuo, Yi-Ru Shen, Hau-Inh Chen, Ying-Hung Lin, Ya-Yun Wang, Yet-Ran Chen, Chia-Yih Wang and Pao-Lin Kuo (2015) SEPT12 orchestrates the formation of mammalian sperm annulus by organizing SEPT12-7-6-2/-4 core complexes, Journal of Cell Science,128,5,pp923-934