首頁師資〉教師指導學生

吳佳慶

吳佳慶  (Wu, Chia-Ching (Josh), Ph.D.)

細胞生物暨解剖學研究所教授   分機:5327

E-mail: joshccwu@mail.ncku.edu.tw

個人網址: http://www.ncku.edu.tw/~anatomy/teachers/CCW.htm

 

研究興趣

1.  以生物力學方法促進幹細胞 (stem cell)與組織工程(tissue engineering)於再生醫學 (regenerative medicine) 的成效

2.  心血管疾病之致病機轉與治療

3.  細胞生物力學 (cellular biomechanics): 細胞機械訊息傳導 (mechanotransduction)及藉由奈米生醫工程技術探討細胞重塑 (cell remodeling)

4.  生醫光電與生物微機電技術 (BioMEMS) 於細胞生物學之應用

 

近五年代表作

 

1. Huang HC, Chang YJ, Chen WC, Harn HI, Tang MJ, Wu CC. (2013) Enhancement of Renal Epithelial Cell Functions through Microfluidic-based Coculture with Adipose-derived Stem Cells., Tissue Eng Part A, online published (SCI)

 

2. Wang CH, Wu CC, Hsu SH, Liou JY, Li YW, Wu KK, Lai YK, Yen BL. (2013) The role of RhoA kinase inhibition in human placenta-derived multipotent cells on neural phenotype and cell survival, Biomaterials, 34, 13,pp 3223-30 (SCI)

 

3. Wu CC, Chen YC, Chang YC, Wang LW, Lin YC, Chiang YL, Ho CJ, Huang CC. (2013) Human umbilical vein endothelial cells protect against hypoxic-ischemic damage in neonatal brain via stromal cell-derived Factor 1/C-X-C chemokine receptor type 4, Stroke, Online Published (SCI)

 

4. Liu C, Tsai AL, Chen YC, Fan SC, Huang CH, Wu CC*, Chang CH* ,2012, Facilitation of human osteoblast apoptosis by sulindac and indomethacin under hypoxic injury, J Cell Biochem,113,1,pp148-55 (SCI)

 

5. Hsueh YY, Chiang YL, Wu CC*, Lin SC* ,2012, Spheroid formation and neural induction in human adipose-derived stem cells on a chitosan-coated surface, Cells Tissues Organs, 196, 2,pp 117-28 (SCI)

 

6. Hung HS, Chu MY, Lin CH, Wu CC, Hsu SH ,2012, Mediation of the migration of endothelial cells and fibroblasts on polyurethane nanocomposites by the activation of integrin-focal adhesion kinase signaling, J Biomed Mater Res A, 100, 1,pp 26-37 (SCI)

 

7. Y.C. Yeh, C.C. Wu, Y.K. Wang, M.J. Tang, DDR1 triggers epithelial cell differentiation by promoting cell adhesion through stabilization of E-cadherin, Mol Biol Cell 22 (2011): 940-953.

 

8. T.J. Chen, C.C. Wu*, M.J. Tang, J.S. Huang, F.C. Su*, Complexity of the tensegrity model for dynamic energy and force distribution of cytoskeleton during cell spreading, PLOS One 12 (2010) e14392. (* Equal correspondence)

 

9. M.L. Sung, C.C. Wu, H.I. Chang, C.K. Yen, H.J. Chen, J.C. Cheng, S. Chien, C.N. Chen, Shear stress inhibits homocysteine-induced stromal cell-derived factor-1 expression in endothelial cells, Circulation Research. (2009) 1524-4571

 

10. H.S. Hung, C.C. Wu, S. Chien, S.H. Hsu, The behavior of endothelial cells on polyurethane nanocomposites and the associated signaling pathways. Biomaterials 30 (2009) 1502-1511

 

11. J.Y. Liou*, C.C. Wu*, S. Lee, B.R. Chen, B.L. Yen, and K.K. Wu, Nonsteroidal anti-inflammatory drugs induced endothelial apoptosis by peroxisome proliferator-activated receptor-d and 14-3-3e transcriptional pathway, Molecular Pharmacology. 74 (2008) 1399-1406 (*Equal 1st author)

12. C.C. Wu, Y.C. Chao, C.N. Chen, S. Chien, Y.C. Chen, C.C. Chien, J.J. Chiu, and B.L. Yen. Synergism of biochemical and mechanical stimuli in the differentiation of human placenta-derived multipotent cells into endothelial cells, J Biomech. 41 (2008) 813-21.