首頁師資〉專/兼任師資專長

司君一

君一 (Chun-I Sze, M.D.)

病理學科 教授   

分機:2648    E-mail: szec@mail.ncku.edu.tw

個人網址:http://www.ncku.edu.tw/~path/sze.htm

 

研究興趣

 

1.      腦腫瘤幹細胞的分離與鑑別;老年癡呆症研究。

2.      學門專長:神經病理。

 

近五年代表作

  1. Sze CI*, Su WP, Chiang MF, Lu CY, Chen YA, Chang NS., 2013, Assessing current therapeutic approaches to decode potential resistance mechanisms in glioblastomas.Front Oncol. 2013;3:59. doi: 10.3389/fonc.2013.00059. Epub 2013 Mar 19.
  2. Chiang MF, Chou PY, Wang WJ, Sze CI, Chang NS., 2013, Tumor Suppressor WWOX and p53 Alterations and Drug Resistance in Glioblastomas. Front Oncol. 2013;3:43. doi: 10.3389/fonc.2013.00043. Epub 2013 Mar 4.
  3. Sze CI, Lin YC, Lin YJ, Hsieh TH, Kuo YM, Lin CH., 2013, The role of glucocorticoid receptors in dexamethasone-induced apoptosis of neuroprogenitor cells in the hippocampus of rat pups. Mediators Inflamm. 2013;2013:628094. doi: 10.1155/2013/628094. Epub 2013 Jan 14.
  4. Huang WSChen CNSze CITeng CC., 2013, Visfatin induces stromal cell-derived factor-1 expression by β1 integrin signaling in colorectal cancer cells. J Cell Physiol. 2013 May;228(5):1017-24.6.
  5. Teng CC, Kuo HC, Cheng HC, Wang TC, Sze CI*., 2012, The inhibitory effect of CIL-102 on the growth of human astrocytoma cells is mediated by the generation of reactive oxygen species and induction of ERK1/2 MAPK. Toxicol Appl Pharmacol, 263(1):73-80
  6. Chang JY, Chiang MF, Lin SR, Lee MH, He H, Chou PY, Chen SJ, Chen YA, Yang LY, Lai FJ, Hsieh CC, Hsieh TH, Sheu HM, Sze CI*, Chang NS., 2012, TIAF1 self-aggregation in peritumor capsule formation, spontaneous activation of SMAD-responsive promoter in p53-deficient environment, and cell death. ,Cell Death Dis. 2012 Apr 26;3:e302. doi: 10.1038/cddis.2012.36.
  7. Teng CC, Yang YT, Chen YC, Kuo YM, Sze C-I*., 2012, Role of WWOX/ WOX1 in Alzheimer’s disease pathology and in cell death signaling., Front Biosci, 1,4, pp1951-1965
  8. Lee JS, Yang CC, Kuo YM, Sze C-I, Hsu JY, Huang YH, Tzeng SF, Tsai CL, Chen HH, Jou IM.,2012, Delayed granulocyte colony-stimulating factor treatment promotes functional recovery in rats with severe contusive spinal cord injury., Spine,37,1,pp10-17
  9. Pugazhenthi S, Wang M, Pham S, Sze CI, Eckman CB. ,2011,Downregulation of CREB expression in Alzheimer's brain and in Aβ-treated rat hippocampal neurons. Mol Neurodegener. 2011 Aug 19;6:60.,6,pp60-75
  10. Teng CC, Sze CI, Wang TC, Lien CY, Liao WC., 2011, Cell line studies of glioblastoma and malignant glioma using a newly discovered prenylated chalcone. Pharm Biol. 2011  Mar;49(3):314-8. Epub 2011 Feb 1.
  11. Lee MH, Lin SR, Chang JY, Schultz L, Heath J, Hsu LJ, Kuo YM, Hong Q, Chiang MF, Gong CX, Sze CI*, Chang NS., 2011, TGF-b induces TIAF1 self-aggregation via type II receptor-independent signaling that leads to generation of amyloid b plaques in Alzheimer’s disease. Cell Death Disease.  2010, 1, e110doi:10.1038/cddis. 2010.83. Correspondent author.
  12. Lee JS, Chang KC, Chen HH, Sze CI*., 2010,Malignant sweat gland tumor presenting as an unusual dural-based lesion: case report, J Neurooncology ,99,2,pp273-276
  13. Li MY, Lai FJ, Hsu LJ, Lo CP, Cheng CL, Lin SR, Lee MH, Chang JY, Subhan D, Tsai MS, Sze CI*, Pugazhenthi S, Chang NS, Chen ST., 2009, Dramatic Co-activation of WWOX/WOX1 with CREB and NF-kappaB in delayed loss of small dorsal root ganglion neurons upon sciatic nerve transaction in rats. Plos One. 2009 Nov 12;4(11):e7820. Contribute equally to the first three authors
  14. Hong Q, Sze C-I, Lin SR, Lee MH, He RY, Schultz L, Chang JY, Chen SJ, Boackle RJ, Hsu LJ, Chang NS., 2009, Complement C1q avtivates tumor suppressor WWOX to induce apoptosis in prostate cancer cells. Plos One 2009; 4: e5775 1-13.